Summary of proteomics and diet information used for comparative evolutionary analysis of rattlesnake venom composition.

Values represent % total venom proteome made up by a given protein as determined by HPLC analyses (see Methods). Abbreviations for names of protein families are as follows: DIS – Disintegrin; LAO – L-amino acid oxidase; CRISP – cysteine rich secretory protein; PLA2– phospholipase A2; SP – serine proteinase; SVMP – snake venom metalloproteinase; svNGF – snake venom nerve growth factor; CTL - C-type lectin-like; MYO – myotoxin; DC – Disintegrin-like/cysteine-rich SVMP C-terminal fragment; PEP - vasoactive peptides; Kunitz - Kunitz-type inhibitor. Diet measures: % mam – proportion of mammals in diet; % liz: proportion of lizards in diet. Taxon names: Sms – Sistrurus m. streckerii; Smm – S. m. milarius; Smb – S. m. barbouri; Sca – S. c. catenatus; Sct – S. c. tergenimus; Sce – S. c. edwardsii; Catrox – Crotalus atrox; Agc – Agkstrodon c. contortrix. Sources for proteomics and diet information are given in the Materials and Methods section.