A Practical Synthesis of (−)-Kainic Acid
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资源简介：
A highly practical stereoselective total synthesis of (−)-kainic acid is described. This synthesis features the stereoselective alkylation of an iodolactone intermediate that was efficiently prepared from (+)-carvone and introduction of carboxylic acid by hydrolysis of a nitrile accompanied by epimerizaion. This synthetic route enabled us to obtain 14.6 g of (−)-kainic acid.
创建时间：
2016-02-23
