Targeting Myc signaling pathway by inhibition of histone demethylase JMJD2B (siRNA)
收藏官方服务：
资源简介：
Targeting Myc signaling pathway by inhibition of histone demethylase JMJD2B (siRNA)
应用场景：
创建时间：
2014-01-01
相关数据集
Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor
The bromodomain containing proteins TRIM24 (tripartite motif containing protein 24) and BRPF1 (bromodomain and PHD finger containing protein 1) are involved in the epigenetic regulation of gene expres
NIAID Data Ecosystem50
Novel chromobox 2 inhibitory peptide decreases tumor progression
The Polycomb Repressor Complex 1 (PRC1) is an epigenetic regulator of differentiation and development, consisting of multiple subunits including RING1, BMI1, and Chromobox. The composition of PRC1 dic
Figshare2023-05-27 更新40
Suppression of the CIC-DUX4 oncogene through p300/CBP inhibition. Suppression of the CIC-DUX4 oncogene through p300/CBP inhibition
A recently identified pediatric subtype of undifferentiated round cell sarcoma that is driven by fusion between the cell cycle regulator and transcriptional repressor, capicula (CIC) and the transcrip
NIAID Data Ecosystem30
HBO1 is required for the maintenance of leukaemia stem cells [shRNA screen]
Acute myeloid leukaemia (AML) is a heterogeneous disease characterised by transcriptional dysregulation resulting in a block in differentiation and increased malignant self-renewal. Various epigenetic
NIAID Data Ecosystem40
Neuroendocrine lineage commitment of small cell lung cancers can be leveraged into p53-independent non-cytotoxic therapy [RNA-seq]. Neuroendocrine lineage commitment of small cell lung cancers can be leveraged into p53-independent non-cytotoxic therapy [RNA-seq]
Small cell lung cancers (SCLC) rapidly resist cytotoxic chemotherapy and immune-checkpoint inhibitor (ICI) treatments. New, non-cross-resistant therapies are thus needed. SCLC cells are committed into
NIAID Data Ecosystem30
