Structures of the human OX1 orexin receptor bound to selective and dual antagonists
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Structures of the human OX1 orexin receptor bound to selective and dual antagonists Descriptor: OLEIC ACID, [5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]{(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl}methanone, human OX1R fusion protein to P.abysii glycogen synthase Authors: Yin, J, Brautigam, C.A, Shao, Z, Clark, L, Harrell, C.M, Gotter, A.L, Coleman, P.J, Renger, J.J, Rosenbaum, D.M. Deposit date: 2015-04-29 Release date: 2016-03-09 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.832 Å) Cite: Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors. Nat.Struct.Mol.Biol., 23, 2016
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2015-04-29
