Source data for Figure 2.2. Spearman’s correlations between DMS datasets generated by the same research group. These alternative DMS datasets include altered selective conditions, different fitnes

NIAID Data Ecosystem70

Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease

靶点验证

深度突变扫描

This record contains supplementary data files related to Deep mutational scanning to characterize the mechanistic role of TYK2 in immune signaling and disease, described below. - tyk2.bcmap-final.

Zenodo2025-10-13 更新40

Deep mutational scanning of human ACE2's interaction with the SARS-Cov-2 spike protein

蛋白质-病毒相互作用

深度突变扫描

We performed deep mutational scanning of human angiotensin-converting enzyme 2 (ACE2) to evaluate how mutations affect recognition by the SARS-CoV-2 spike protein.

NIAID Data Ecosystem80

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

病毒与抗病毒蛋白功能分析

抗病毒纳米抗体

Of the 16 non-structural proteins (Nsps) encoded by SARS CoV-2, Nsp3 is the largest and plays important roles in the viral life cycle. Being a large, multidomain, transmembrane protein, Nsp3 has been

NIAID Data Ecosystem60

Probing the functional constraints of influenza A virus NEP by deep mutational scanning

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