Correlations between various ENM-predicted covariances and those observed in NMR experiments^(a).

(a)Results obtained for the test set of proteins listed in Table S2. (b)Symbols used are: U – Uniform (γ = 1) force constant; D - distance-dependent (γ = 1/d2) force constant; γ(1) – Nearest neighbor interactions are increased by a factor of 10; γ(2) – Second neighbor interactions are changed by a factor of −1 in U models or −5 in D models; HB – Interactions between residues joined by backbone hydrogen bonds are increased by a factor of 10. Values by protein can be found in Table S3.