Comparative transcriptome analysis of different pancreatic cancer cells

NIAID Data Ecosystem2026-05-01 收录

胰腺癌耐药机制

转录组学与代谢调控

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资源简介：

Exosomal ACADM sensitizes gemcitabine-resistance through modulating fatty acid metabolism and ferroptosis in pancreatic cancer

创建时间：

2023-06-16

Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition [RNA-Seq]

胰腺癌耐药机制

CRISPRi功能基因组学

Over expression of co-repressor complexes implicated as a cause of multiple drug resistance in pancreatic cancer. Genome-wide CRISPR activation and knockout screen in pancreatic cancer cell lines

NIAID Data Ecosystem140

DNA methylation data of PAC PDX models after Gemcitabine treatment

胰腺癌耐药机制

甲基化DNA生物标志物

Purpose: Gemcitabine is most commonly used for pancreatic cancer (PC). However, the molecular features and mechanisms of the frequently occurred resistance remain unclear. This work aims at exploring

NIAID Data Ecosystem50

Transcriptomic analysis of Panc10.05 cells treated with indisulam

胰腺癌耐药机制

药物转录组学

Indisulam is an abandoned drug that acts as a molecular glue, inducing degradation of splicing factor RBM39 through interaction with CRL4DCAF15. We generated spontaneoulsy indisulam-resistant Panc10.0

NIAID Data Ecosystem30

Additional file 1: of FBP1 loss contributes to BET inhibitors resistance by undermining c-Myc expression in pancreatic ductal adenocarcinoma

胰腺癌耐药机制

表观遗传调控

Figure S1. BRD2, BRD3 or BRD4 make no effect on the expression of FBP1. Table S2. Sequences for shRNAs. (ZIP 272Â kb)

NIAID Data Ecosystem110

Effects of a quadruplex-binding compound on gemcitabine resistant pancreatic cancer cells

胰腺癌耐药机制

RNA-seq转录组学

Changes in gene expression in a pancreatic cancer cell line and a chemoresistant line on treating with the drug CM03 Overall design: Changes at 6 h and 24 h were evaluated with RNA-seq with respect to

NIAID Data Ecosystem40

Comparative transcriptome analysis of different pancreatic cancer cells

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