Small RNAs (sRNAs) can operate as regulatory agents to control protein expression by interaction with the 5′ untranslated region of the mRNA. We have developed a physicochemical framework, relying on

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Oligonucleotides sequence encoding 53R-specific pre-miRNAs.

RNA设计

基因沉默序列

Bold letters represent sense sequences of engineered amiRNAs derived from the target gene.

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Additional file 11 of Design of siRNA molecules for silencing of membrane glycoprotein, nucleocapsid phosphoprotein, and surface glycoprotein genes of SARS-CoV2

病毒基因沉默

siRNA药物设计

Additional file 11: Supplementary Table 11. List of siRNAs predicted by i-Score Designer for various conserved regions of the 'N' gene

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siRNA sequences used in this study.

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