Mpe1 senses the binding of pre-mRNA and controls 3'-end processing by CPF. Rodríguez-Molina et al
收藏NIAID Data Ecosystem2026-03-13 收录
官方服务:
资源简介:
This entry contains raw data including electrophoresis gels, chromatograms, RT-qPCR,
应用场景:
创建时间:
2022-07-04
相关数据集
Alternative RNA Stuctures Formed During Transcription Depend on Elongation Rate and Modify RNA processing
Most RNA processing occurs co-transcriptionally. We interrogated nascent pol II transcripts by chemical and enzymatic probing, and determined how the ânascent RNA structureomeâ relates to splicing
NIAID Data Ecosystem90
Structural characterization of the 3'-end pre-mRNA processing complex CStF
The main goal of this proposal is to build a comprehensive understanding of a new layer of eukaryotic 3’-end precursor-mRNA processing, with focus on the Cleavage Stimulation Factor (CStF) complex. Th
DataCite Commons2025-09-28 更新30
Elevated pre-mRNA 3' end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation [ChrRNA-seq]. Elevated pre-mRNA 3' end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation [ChrRNA-seq]
Cleavage and polyadenylation (CPA) defines the 3’ end of almost all eukaryotic mRNAs. CPA inhibition, or CPAi, leads to transcriptional readthrough. Here, we show that the CPSF-73 inhibitor JTE-607 gl
NIAID Data Ecosystem20
CPSF6 regulates alternative polydenylation and proliferation of cancer cell through phase separation Ⅱ. CPSF6 regulates alternative polydenylation and proliferation of cancer cell through phase separation Ⅱ
To verify the effect of phosphorylation of CPSF6 by CLK2 on APA, we co overexpressed CLK2 and wild-type CPSF6 or phosphorylated mutant CPSF6 in HEK293T cells Overall design: Compare the changes in APA
NIAID Data Ecosystem80
MicroRNA Clustering Assists Processing of Suboptimal MicroRNA Hairpins Through the Action of the ERH Protein. Fang and Bartel
Microprocessor initiates processing of microRNAs (miRNAs) from hairpin regions of primary transcripts (pri-miRNAs). Pri-miRNAs often contain multiple miRNA hairpins, and this clustered arrangement can
Mendeley Data2020-04-04 更新30



