Average costs per person, average QALY per person with 95% confidence limits, and the proportion of the results of the simulations per quadrant of the cost-effectiveness plane after 20-years Overall result: weighted average with weights according to the proportion of patients in the different gender and age categories undergoing TKA in the Netherlands [22].

Proportions CE-plane: The North-East (NE) quadrant indicates that the KJD strategy is more effective but also more costly than the TKA strategy. A result in the South East (SE) quadrant means that KJD is dominant. A result in the South West (SW) quadrant means that KJD is less costly but also less effective, and a result in the North West (NW) quadrant means that KJD is less effective and more costly (inferior).