3.15A structure of QPT-1 with S.aureus DNA gyrase and DNA
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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3.15A structure of QPT-1 with S.aureus DNA gyrase and DNA Descriptor: (2R,4S,4aS)-4',6'-dihydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidin]-2'-one, (2R,4S,4aS,5R)-6'-hydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4'(3'H)-dione, (2R,4S,4aS,5S)-6'-hydroxy-2,4-dimethyl-8-nitro-1,2,4,4a-tetrahydro-2'H,6H-spiro[1,4-oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4'(3'H)-dione, ... Authors: Bax, B.D, Srikannathasan, V, Chan, P.F. Deposit date: 2015-07-04 Release date: 2015-12-16 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin. Nat Commun, 6, 2015
创建时间：
2015-07-04
