Analysis for stimulatory and inhibitory motifs in Trypanosomatidae and vertebrate genomes.

Stimulatory motifs (RRCGYY for [purin-purin-C-G-pyrimidin-pyrimidin]; HRWCGTTN for [(notG)-purin-(A or T)-C-G-T-T-any base] and inhibitory motifs (WKKVGGGG for [(A or T)-(G or T)-(G or T)-(A or C or T)-G-G-G-G]; CCNDDNNGGG for [C-C-x-(notC)-(notC)-x-x-G-G-G], where × stands for any base) were searched in whole genomes. For each motif, the counted number was indicated as the observed number. The expected motif number was calculated as (motif frequency × genome size). The motif frequency corresponds to the product of frequency for each nucleotide, which is different from one genome to another (Table S1). The rO/E corresponds to the ratio between the observed number and the expected number of the motifs.Analysis for stimulatory and inhibitory motifs in Trypanosomatidae and vertebrate genomes.