Enantioselective Synthesis of Cephalimysins B and C
收藏NIAID Data Ecosystem2026-03-10 收录
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The first synthesis of cephalimysins B and C is reported. The route features a Ni(II)–diamine-catalyzed enantioselective conjugate addition of a densely substituted 3(2H)-furanone and an efficient dihydroxylation–lactonization sequence as key steps in the assembly of the spirocyclic core. The fully synthetic strategy is amenable to analog preparation.
创建时间：
2017-02-03
