Plasmid-mediated dissemination of ISL3 giving rise to colistin-resistance in KPC-producing Klebsiella pneumoniae
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https://www.ncbi.nlm.nih.gov/sra/ERP021876
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资源简介：
Mcr-1 has been reported as first plasmid gene to confer colistin-resistance. In KPC-producing Klebsiella pneumoniae (KPC-KP) isolates, however, colistin resistance is rapidly emerging through other mechanisms. This is frequently the result of inactivation of mgrB by insertion sequences, for instance ISL3. The aim of this study is to identify localization and targets of ISL3 sequences by next generation sequencing of successful KPC-KP lineages.
创建时间：
2023-04-26
