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JAL-TA9 and GSGFR cleaves amyloid beta fragment peptides

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NIAID Data Ecosystem2026-03-14 收录
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Time-dependent analysis of the reaction mixtures of JAL-TA9 and Aβ11-29. 0.05 mM Aβ11-29 was incubated either (a) without or (b) with 0.2 mM JAL-TA9. 0.05 mM Aβ11-29 was incubated either (c) without or (d) with 0.2 mM GSGFR.The reaction mixtures were analyzed by HPLC. Peaks observed after incubation were fractionated and applied by ESI-MS analysis. Cleavage sites were summarized (e) and (f).

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2022-10-19
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