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Structure of C81R Mutant PCNA Protein Defective in Mismatch Repair

NIAID Data Ecosystem2026-05-01 收录

蛋白质结构生物学

DNA错配修复

数据链接：

https://www.rcsb.org/structure/4L60 数据链接链接失效反馈

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Structure of C81R Mutant PCNA Protein Defective in Mismatch Repair

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创建时间：

2023-09-20

DNA错配修复

DNA复合物

Crystal Structure of the MutS-ADPBeF3-DNA complex Descriptor: 1,2-ETHANEDIOL, 5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3', 5'-D(P*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*

Protein Data Bank Japan2024-02-14 更新60

Anti-recombination function of MutSa restricts telomere extension by ALT-associated homology directed repair.

端粒替代延长

DNA错配修复

Alternative lengthening of telomeres (ALT) is a telomere elongation mechanism observed in ~15% of cancer subtypes. Current models indicate that ALT is mediated by homology-directed repair mechanisms.

NIAID Data Ecosystem40

The structure of thiocyanate dehydrogenase mutant form with Thr 169 replaced by Ala from Thioalkalivibrio paradoxus

蛋白质结构生物学

突变体分析

The structure of thiocyanate dehydrogenase mutant form with Thr 169 replaced by Ala from Thioalkalivibrio paradoxus

NIAID Data Ecosystem40

FtsA (apo form) from Thermotoga maritima

蛋白质结构生物学

细胞分裂机制

FtsA (apo form) from Thermotoga maritima

NIAID Data Ecosystem50

mouse exome. Mus musculus

外显子测序

DNA错配修复

Whole exome sequencing of WT and Msh2-/- MEFs at each stage was performed and analyzed. Samples were prepared from WT and Msh2-/- MEFs at each stage based on the protocol (Agilent).

NIAID Data Ecosystem40

Structure of C81R Mutant PCNA Protein Defective in Mismatch Repair

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