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Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) table for Placenta Full Term, v1.0

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DataCite Commons2025-09-11 更新2024-07-13 收录
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https://entity.api.hubmapconsortium.org/redirect/HBM446.WGLG.755
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[Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) tables](https://humanatlas.io/asctb-tables) aim to<br>capture the nested *part_of* structure of anatomical human body parts, the typology of cells, and biomarkers used to<br>identify cell types. The tables are authored and reviewed by an international team of experts. The Placenta ASCT+B<br>table represents terms related to the full term human placenta. These include both macroscopic and microscopic<br>anatomical structures, major cell types, and protein and lipid biomarkers specific for each cell type listed. This<br>table was generated based on published placental histopathologic nomenclature, as well as published literature on<br>cell-type specific biomarkers. Most of the markers listed are observed in more than 1 study or orthogonally<br>validated. Note that these are predicted markers and a single marker to annotate a cell type is not likely sufficient<br>or specific. Where more refined cell types are not available in the ontologies, the closest general term is used. For<br>example, there are likely multiple types of placental stromal cells; however, further characterization is needed to<br>distinguish between these cell types. Where cells of similar type occur in different locations, the closest and<br>highest level of resolution available is used. For example, vascular endothelial cells (CL0000071) occur in multiple<br>different contexts within the placenta, including the umbilical vessels, chorionic plate vessels, chorionic stem<br>villous vessels and capillaries, and decidual vessels; similarly, vascular smooth muscle cells (CL0000359) occur in<br>umbilical vessels, chorionic plate vessels, and chorionic stem villous vessels.
提供机构:
HuBMAP
创建时间:
2022-07-27
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