Replication Data for: Simulated burn pit smoke condensates cause transient impact on human airway epithelial cells

Inhalation of smoke from burn pits during military deployment is associated with several adverse pulmonary outcomes. We have demonstrated that acute exposure to simulated burn pit waste (BPW) smoke condensates modifies cellular processes in cultured human airway epithelial cells (HAEC). In the present study, we examined gene regulation by single and repeated exposure to lower dose of BPW smoke condensates and whether these changes persisted 48 hrs post-exposure. BPW source material (cardboard and plastic), combustion condition (smoldering and flaming), and biological sex influenced HAEC gene expression changes. Collectively, we demonstrate that BPW smoke may cause long-lasting impact on HAECs.