Salvia miltiorrhiza-derived Nanovesicles Reshape Gut Microbial Ecology to Attenuate Atherosclerosis: A Synergy of Nano-Phytotherapy and Microbial Metabolomics
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP582506
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SDNVs represent a multi-target therapeutic strategy that (1) remodels gut microbiota composition, (2) disrupts the TMA-TMAO axis via miRNA-mediated CutC silencing, and (3) mitigates vascular inflammation. Their scalable production, gastrointestinal specificity, and dual modulation of microbial-host interactions position SDNVs as a promising candidate for clinical translation in microbiota-driven cardiovascular diseases.
创建时间：
2025-05-02
