Proximal TCR signaling by endogenous self-peptides modifies gene expression without amplifying distal signaling in CD4 T cells
收藏NIAID Data Ecosystem2026-05-02 收录
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The goal of the study was to characterize the molecular signatures of lymph node T cell of TCR transgenic mouse under different treatment. We compared the transcriptome profiles of mouse lymph node T cells under different treatment (NP (no peptide), GP (self-peptide), MCC (agonist), GP+MCC). Overall design: Mouse lymph node T cell populations were sorted and whole transcriptome analysis was performed using an Illumina NovaSeq 6000 machine
创建时间：
2025-05-20
