Additional file 6: Table S2. The overlapped genes of modules correlating with NPM1 significantly, by analysis based on TCGA and BeatAML database, respectively.
Whole genome sequencing of AML blood or bone marrow at presentation and remission for 5 patients. Relapse samples are included for 2 patients, totaling 12 WGS BAM files.EGA dataset EGAD00001005120
RNA sequencing of human leukemia Overall design: The goals of this project are to obtain a comprehensive study of mutations and gene expression in human acute myeloid leukemia (AML). Methods: AML cell
Acute myeloid leukaemia (AML) is a heterogeneous haematological malignancy caused by mutations in genes encoding transcriptional and epigenetic regulators together with signalling genes. It is charact
Mutations affecting NPM1 define the commonest subgroup of acute myeloid leukemia (AML). They frequently co-occur with mutations of FLT3, usually internal tandem duplications (ITD), and less commonly o
