LSD1-CoREST in complex with AW2, long soaking
收藏Protein Data Bank Japan2025-06-25 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8f30
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LSD1-CoREST in complex with AW2, long soaking Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-{5-[3-([1,1'-biphenyl]-4-yl)propanoyl]-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl}-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) Authors: Caroli, J, Mattevi, A. Deposit date: 2022-11-09 Release date: 2024-06-12 Last modified: 2025-06-25 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance. Nat Commun, 16, 2025
创建时间：
2022-11-09
