Tricomplex of RMC-7977, NRAS WT, and CypA
收藏Protein Data Bank Japan2024-06-05 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8tbi
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Tricomplex of RMC-7977, NRAS WT, and CypA Descriptor: (1R,5S,6r)-N-[(1P,7S,9S,13S,20M)-20-{5-(4-cyclopropylpiperazin-1-yl)-2-[(1S)-1-methoxyethyl]pyridin-3-yl}-21-ethyl-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-3-oxabicyclo[3.1.0]hexane-6-carboxamide, GTPase NRas, MAGNESIUM ION, ... Authors: Tomlinson, A.C.A, Chen, A, Knox, J.E, Yano, J.K. Deposit date: 2023-06-28 Release date: 2024-02-07 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature, 629, 2024
创建时间：
2023-06-28
