Engineering of high-precision C-to-G base editors with expanded site selectivity and target compatibility
收藏NIAID Data Ecosystem2026-05-02 收录
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资源简介：
By systematic exploration of deaminases to construct CGBEs, we have identified CDA1-based CGBEs that exhibit a distinct preference for editing position 3. Furthermore, we report that truncations of the CDA1 C-terminus significantly enhance the efficiency of C-to-G editing by CGBEs.
创建时间：
2024-11-26
