AKR1C3

ENCODES a protein that exhibits 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity (ortholog); aldo-keto reductase (NADPH) activity (ortholog); aldose reductase (NADPH) activity (ortholog); INVOLVED IN cellular response to follicle-stimulating hormone stimulus (ortholog); cellular response to forskolin (ortholog); cellular response to gonadotropin-releasing hormone (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); castration-resistant prostate carcinoma (ortholog); FOUND IN cytosol (ortholog)

编码一种表现出17-α,20-α-二羟基孕-4-烯-3-酮脱氢酶[NAD(P)+]活性（同源酶）；醛酮还原酶（NADPH）活性（同源酶）；醛糖还原酶（NADPH）活性（同源酶）；参与细胞对促卵泡激素刺激的应答（同源酶）；对 forskolin 的细胞应答（同源酶）；对促性腺激素释放激素的细胞应答（同源酶）；参与阿司匹林药代动力学途径；抗吡啉药物途径；花生四烯酸代谢途径；与自闭症谱系障碍（同源酶）相关；与B-淋巴细胞白血病/淋巴瘤（同源酶）相关；与去势抵抗性前列腺癌（同源酶）相关；存在于细胞质中（同源酶）