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Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound

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Protein Data Bank Japan2023-08-23 更新2026-03-21 收录
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https://pdbj.org/mine/summary/1tg2
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Crystal structure of phenylalanine hydroxylase A313T mutant with 7,8-dihydrobiopterin bound Descriptor: 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, FE (III) ION, Phenylalanine-4-hydroxylase Authors: Erlandsen, H, Pey, A.L, Gamez, A, Perez, B, Desviat, L.R, Aguado, C, Koch, R, Surendran, S, Tyring, S, Matalon, R, Scriver, C.R, Ugarte, M, Martinez, A, Stevens, R.C. Deposit date: 2004-05-28 Release date: 2004-11-30 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. Proc.Natl.Acad.Sci.Usa, 101, 2004
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2004-05-28
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