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EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3lzb
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资源简介:
EGFR kinase domain complexed with an imidazo[2,1-b]thiazole inhibitor Descriptor: Epidermal growth factor receptor, N-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide Authors: Swinger, K.K. Deposit date: 2010-03-01 Release date: 2011-03-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases. Bioorg.Med.Chem.Lett., 20, 2010
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2010-03-01
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