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Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of hTEAD2 in complex with a trisubstituted pyrazole inhibitor Descriptor: MYRISTIC ACID, Transcriptional enhancer factor TEF-4, ethyl 1-(4-azanylbutyl)-3-(3,4-dichlorophenyl)pyrazole-4-carboxylate Authors: Sturbaut, M, Allemand, F, Guichou, J.F. Deposit date: 2019-07-03 Release date: 2020-07-22 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors. Eur.J.Med.Chem., 226, 2021

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2019-07-03
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