Transcriptomic analysis of human B cell responses to vaccination
收藏官方服务：
资源简介：
Transcriptomic analysis of human B cell responses to vaccination
应用场景：
创建时间：
2015-12-31
相关数据集
Transcriptional profiling of HBV-naïve subjects before vaccination against Hepatitis A/B viruses, Diphtheria/Tetanus toxoids and Cholera.
Mechanisms of poor responses to vaccines remain unknown. Hepatitis B virus-naïve elderly subjects received three vaccines, including a vaccine against hepatitis B virus (HBV). Pre-vaccination high dim
NIAID Data Ecosystem20
Production by activated human T cells of interleukin 4 but not interferon-gamma is associated with elevated levels of serum antibodies to activating malaria antigens.
T cells play a crucial role in antibody-mediated and antibody-independent immunity against Plasmodium falciparum malaria. Therefore, a vaccine immunogen should include parasite-derived B- and T-cell e
PubMed Central00
BCG-2 IGK/IGL
After the mice were immunized with BCG once, the B cell receptor (BCR) IGK/IGL in the mouse spleen was subsequently assessed.
NIAID Data Ecosystem00
Table 2_Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngotracheitis virus.docx
A glycoprotein-G-deleted live-attenuated vaccine strain of the infectious laryngotracheitis virus (ILTV), ΔgG-ILTV, is safe and efficacious against ILTV challenge. In the current study, the transcript
NIAID Data Ecosystem10
Merck Ad5/HIV induces broad innate immune activation that predicts CD8_ T-cell responses but is attenuated by preexisting Ad5 immunity.
To better understand how innate immune responses to vaccination can lead to lasting protective immunity, we used a systems approach to define immune signatures in humans over 1 wk following MRKAd5/HIV
NIAID Data Ecosystem00
