Multivariate analysis of main and joint effects of <i>MCP-1</i> and <i>MMP-1</i> tuberculosis susceptibility genotypes in Peruvians.

AGroups were compared using multiple logistic regression analysis. In the annotations for combinations of genotype at the two loci under study, the MCP-1 genotype is listed first followed by the MMP-1 genotype. Individuals carrying MCP-1 genotypes AA or AG were grouped under the A/- denomination. Individuals carrying MMP-1 genotypes 1G/1G or 1G/2G were grouped under the 1G/- denomination. The following is an example of annotations of combination genotypes at the two loci studied: A/- 1G/- refers to individual carriers of a genotype AA or AG at the MCP-1 locus and a genotype 1G/1G or 1G/2G at MMP-1 locus. BTB = New cases of pulmonary TB. CPPD+ = Healthy tuberculin reactors. DOR = Odds ratio, CI = Confidence interval.