A convenient method of aligning large DNA molecules on bare mica surfaces for atomic force microscopy.
收藏PubMed Central1998-10-15 更新2026-05-25 收录
下载链接：
https://pmc.ncbi.nlm.nih.gov/articles/PMC147909/
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资源简介：
Large DNA molecules remain difficult to be imaged by atomic force microscopy (AFM) because of the tendency of aggregation. A method is described to align long DNA fibers in a single direction on unmodified mica to facilitate AFM studies. The clear background, minimal overstretching, high reproducibility and convenience of this aligning procedure make it useful for physical mapping of genome regions and the studies of DNA-protein complexes.
创建时间：
1998-10-15
