Cigarette smoke silences innate lymphoid cell function in the lung, facilitating an IL-33-dependent, exacerbated Th-1 response to infection. Mus musculus

Using gene expression profiling to examine how IL33 treatment affect gene expression in lung tissues of mice Overall design: Mice were exposure to cigarette smoke or room air and treated with intranasal IL-33 or PBS, the lung tissues then subjected to microarray analysis to examine the gene expression profiles