Crystal structure of human glutaminyl cyclase variant Y115E-Y117E in complex with SEN177
收藏Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal structure of human glutaminyl cyclase variant Y115E-Y117E in complex with SEN177 Descriptor: 1,2-ETHANEDIOL, 2-fluoranyl-5-[2-[4-(4-methyl-1,2,4-triazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyridine, Glutaminyl-peptide cyclotransferase, ... Authors: Pozzi, C, Di Pisa, F, Benvenuti, M, Mangani, S. Deposit date: 2018-04-16 Release date: 2018-09-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.72 Å) Cite: The structure of the human glutaminyl cyclase-SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders. J. Biol. Inorg. Chem., 23, 2018
创建时间：
2018-04-16
