Rhodium-Catalyzed Asymmetric Arylation/Defluorination of 1‑(Trifluoromethyl)alkenes Forming Enantioenriched 1,1-Difluoroalkenes
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https://figshare.com/articles/dataset/Rhodium-Catalyzed_Asymmetric_Arylation_Defluorination_of_1_Trifluoromethyl_alkenes_Forming_Enantioenriched_1_1-Difluoroalkenes/3841047
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资源简介：
The
reaction of 1-(trifluoromethyl)alkenes (CF3CH=CHR)
with arylboroxines (ArBO)3 in the presence of a chiral
diene-rhodium catalyst gave high yields of chiral 1,1-difluoroalkenes
(CF2=CHC*HArR) with high enantioselectivity (≥95%
ee). The reaction is assumed to proceed through β-fluoride elimination
of a β,β,β-trifluoroalkylrhodium intermediate that
is generated by arylrhodation of the 1-(trifluoromethyl)alkene.
创建时间：
2016-09-22
