Expression data from heat-damaged MHCC97H treated by HGF. Expression data from heat-damaged MHCC97H treated by HGF

Incomplete heat-damaged MHCC97H ususlly recurred. The mechanism of how residual HCC cells survive sublethal heat stress and develop rapid outgrowth remains poorly understood. We used microarrays to detail the gene expression and identified distinct classes of up-regulated and downregulated genes under the treatment of HGF at different dosages. Overall design: Sample from heat-damaged MHCC97H treated by HGF for RNA extraction and hybridization on Affymetrix microarrays. We sought to identified distinct classes of up-regulated and downregulated genes during this process. To that end, we compared differential genes among three groups: heat-damaged MHCC97H treated by HGF at 0 ng/ml, 2ng/ml, 10ng/ml.