Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma [CRISPR screen]
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资源简介：
Investigation of epigenetic regulators that module hypomethylating agent response in T-cell lymphoma. CRISPR/Cas9 screen in T-cell lymphoma cell line (Hut78). Hut78 Cas9 cells were transduced with a library of sgRNAs targeting epigenetic regulators and treated with DMSO, Azacitidine (300nM) or Guadecitabine (150nM) for 24 days. Drop-out and enrichment analysis was performed.
创建时间：
2022-04-23
