Predicted impact of mutations (sequence-based).
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ConSurf conservation scores: 1 (variable) to 9 (highly conserved). Jalview conservation scores: 0 (variable) to 11 (highly conserved). SCPred: residue serves as a stabilization center (“yes”) or not (“no”). N = neutral, P = pathogenic, ? = unclassified. *prediction unreliable at 0.95 probability level.
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2015-12-02



