IntroductionAlpha-synuclein (α-Syn) aggregation, transmission, and contribution to neurotoxicity represent central mechanisms underlying Parkinson’s disease. The plant alkaloid “nicotine” was reported
Octopamine is a well-established invertebrate neurotransmitter involved in fight-or-flight responses. In mammals, its function was replaced by norepinephrine. Nevertheless, it is present at trace amou
Raw data from the paper Experimental ischemic stroke-induced alpha-synuclein pathology enhances endothelial inflammatory response and impairs angiogenesis
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series from fibroblasts, iPSCs and neurons with four copies of SNCA, and equivalent cell lines from an u
The accumulation of alpha-synuclein (aSyn) is the hallmark of a group of neurodegenerative conditions termed synucleopathies. Physiological functions of aSyn, including those outside of the CNS, remai
