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The origins and vulnerabilities of two transmissible cancers in Tasmanian devils (2018).

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP024208
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资源简介:
Transmissible cancers are clonal lineages that spread through populations via contagious cancer cells. Although rare in nature, two distinct facial tumour clones - DFT1 and DFT2 - affect Tasmanian devils. In this study, we performed a comparative genomic characterisation of these lineages. This set entails high-coverage whole genome sequencing (WGS) data aligned to the Tasmanian devil reference genome 7.1, in BAM format: two DFT1 tumours sampled in 2005 (86T, coverage: 86X) and 2007 (88T, coverage: 67X), two DFT2 tumours sampled in 2014 (202T2, coverage: 67X and 203T3, coverage: 70X), as well as four normal devils sampled in 2006 (91H, coverage: 65X), 2007 (31H, coverage: 17X), and 2014 (202H1, coverage: 49X and 203H, coverage: 45X). Please cite our paper relating to this data: Stammnitz, M.R. et al. "The origins and vulnerabilities of two transmissible cancers in Tasmanian devils". Cancer Cell 33(4), 607-619 (2018).
创建时间:
2023-04-26
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