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Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP and Tomudex

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal Structure of C.elegans Thymidylate Synthase in Complex with dUMP and Tomudex Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase Authors: Wilk, P, Jarmula, A, Maj, P, Dowiercial, A, Banaszak, K, Rypniewski, W, Rode, W. Deposit date: 2017-04-12 Release date: 2017-05-03 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS. J. Mol. Graph. Model., 77, 2017
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2017-04-12
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