Objective: This study examined whether clinical data routinely available in a computerized patient record (CPR) can be used to drive a complex guideline that supports physicians in real time and at th
BackgroundDrug-disease interactions negatively affect the benefit/risk ratio of drugs for specific populations. In these conditions drugs should be avoided, adjusted, or accompanied by extra monitorin
BackgroundClinical pharmacy services and clinical decision support systems (CDSSs) are increasingly implemented to optimize medication safety. However, risks as overalerting can limit these benefits.
Prostate specific antigen (PSA) is widely used as a diagnostic biomarker for prostate cancer (PC). However, due to its low predictive performance, many patients without PC suffer from the harms of unn