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Intergrated Multi-omics Sequencing Reveals Metabolic Reprograms in the Progression of ccRCC_spatial_multiome

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Mendeley Data2026-04-09 收录
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100 samples from treatment-naive ccRCC patients and 50 matched normal adjacent tissues (NATs) were profiled with whole exon sequencing (WES), whole transcriptome sequencing (WTS), data-independent acquisition (DIA)-based proteome and untargeted metabolome technology to identify the general molecular characteristics of the TJ-RCC cohort. Single-nucleic RNA sequencing, single-nucleic multiome, spatial transcriptome and spatial metabolome were performed on part of these 100 tumors to detail the ITH inside ccRCC.
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Junyi Hu
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