一种催化制备UDP-鼠李糖的融合酶及其应用

获得了一种能实现辅酶自循环而催化UDP-葡萄糖生成UDP-鼠李糖的融合酶VvRHM-NRS，在反应体系中只需在起始阶段添加少量的NAD+，无需加入 NADPH，就可生成UDP-鼠李糖，这是首次能实现辅 酶自循环而合成UDP-鼠李糖。

A fusion enzyme VvRHM-NRS capable of mediating coenzyme self-circulation to catalyze the conversion of UDP-glucose into UDP-rhamnose was obtained. In the reaction system, only a small amount of NAD+ needs to be added at the initial stage, with no NADPH required, to produce UDP-rhamnose. This represents the first report of achieving coenzyme self-circulation for the biosynthesis of UDP-rhamnose.

搜集汇总

背景与挑战

背景概述

该数据集涉及一种催化制备UDP-鼠李糖的融合酶VvRHM-NRS及其应用。该融合酶能实现辅酶自循环，在起始阶段仅需少量NAD+即可从UDP-葡萄糖生成UDP-鼠李糖，无需加入NADPH。