Alternative lengthening of telomeres (ALT) is a telomere elongation mechanism observed in ~15% of cancer subtypes. Current models indicate that ALT is mediated by homology-directed repair mechanisms.

NIAID Data Ecosystem40

MMR gene alterations in cancer cell lines with determined MSI status.

肿瘤基因组学

DNA错配修复

Counts indicate the number of missense mutations in MMR genes, and cells with text in bold correspond to indels found in MMR genes.

Figshare2015-12-02 更新30

Crystal Structure of the MutS-ADPBeF3-DNA complex

DNA错配修复

DNA复合物

Crystal Structure of the MutS-ADPBeF3-DNA complex Descriptor: 1,2-ETHANEDIOL, 5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3', 5'-D(P*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*

Protein Data Bank Japan2024-02-14 更新60

mouse exome. Mus musculus

外显子测序

DNA错配修复

Whole exome sequencing of WT and Msh2-/- MEFs at each stage was performed and analyzed. Samples were prepared from WT and Msh2-/- MEFs at each stage based on the protocol (Agilent).

NIAID Data Ecosystem40

Saccharomyces cerevisiae W303 Genome sequencing. Saccharomyces cerevisiae W303

资源简介：

相关数据集