Genome-wide identification of 5hmCpGs in multiple myeloma
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https://www.ncbi.nlm.nih.gov/sra/SRP174036
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资源简介：
We report the genomic localization of 5-hydroxymethylcytosines in multiple myeloma patients through the use of selective chemical labeling (SCL) and exonuclease digestion. Data highlighted super-enhancers and enhancers specifically undergoing active DNA demethylation in multiple myeloma cells. Overall design: Genomic DNA from multiple myeloma (MM) cells was extracted and submitted to the SCL-exo protocol. After sequencing with a HiSeq 1500 (Illumina), reads were mapped to hg19 and processed to generate a single-CpG signal file (wig file) indicating the relative levels of hydroxymethylation.
创建时间：
2019-09-24
