Two new chromones from <i>Portulaca oleracea</i> L. and their bioactivities

Two new chromones, oleracone H (<b>1</b>) and oleracone I (<b>2</b>), were isolated from <i>Portulaca oleracea</i> L. and identified by UV, IR, UHPLC-ESI-QTOF/MS, 1D NMR, 2D NMR, and CD spectra. In 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical quenching assay, oleracone H (<b>1</b>) and oleracone I (<b>2</b>) presented scavenging activities with IC₅₀ values (half maximal inhibitory concentration) of 16.33 ± 0.20 μM and 22.36 ± 0.41 μM and the abilities of inhibiting the inflammatory factors IL-1<i>β</i> and TNF-<i>α</i> of the two compounds were superior to that of the positive control at 10 μM.