Various DNA damage parameters to assess the genotoxic effect of N-OH-AABP.

Figshare2015-12-02 更新2026-04-29 收录

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Various DNA damage parameters to assess the genotoxic effect of N-OH-AABP.

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2015-12-02

Additional file 3: of Guide RNAs with embedded barcodes boost CRISPR-pooled screens

CRISPR组合筛选

基因毒性评估

Table S4. Results of the human genome-scale sgRNAiBAR library screening at different MOI for the cytotoxicity of TcdB using conventional MAGeCK analysis. Table S5. Results of the human genome-scale sg

NIAID Data Ecosystem100

Genome-wide profiling reveals the distribution pattern of abasic sites in mammalian genomes. Genome-wide profiling reveals the distribution pattern of abasic sites in mammalian genomes

DNA损伤检测

基因组稳定性研究

The AP-seq provides a genome-wide method for detecting abasic sites among the human and mouse genomes Purpose: Abasic sites are one of the most frequent DNA damage among the genome , which often carri

NIAID Data Ecosystem60

Complex Genomic Patterns of Abasic Sites in Mammalian DNA Revealed by High-Resolution SSiNGLe-AP Method. Complex Genomic Patterns of Abasic Sites in Mammalian DNA Revealed by High-Resolution SSiNGLe-AP Method

DNA损伤检测

基因组稳定性

DNA damage plays critical role in biology and disease, however, precise understanding of how different types of DNA damage affect cellular functions is far from clear. A major underlying reason for th

NIAID Data Ecosystem40

Comet Assay-final % numbers

DNA损伤检测

彗星试验

The values representing percentage DNA in comet tail are listed for all measured comets. The means/standard deviations of each group were used to make the graph.

DataCite Commons2025-04-01 更新100

Assessment of the Performance of the TGx-DDI Biomarker to Detect DNA Damage-Inducing Agents Using Quantitative RT- PCR in TK6 Cells. Assessment of the Performance of the TGx-DDI Biomarker to Detect DNA Damage-Inducing Agents Using Quantitative RT- PCR in TK6 Cells

基因毒性评估

转录组生物标志物验证

Gene expression biomarkers are now available for application in the identification of genotoxic hazards. The TGx-DDI transcriptomic biomarker can accurately distinguish DDI from non-DDI exposures base

NIAID Data Ecosystem50

Various DNA damage parameters to assess the genotoxic effect of N-OH-AABP.

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