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BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia

NIAID Data Ecosystem2026-05-01 收录

幼年型粒单核细胞白血病治疗

药物协同效应评估

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP458773 数据链接链接失效反馈

官方服务：

资源简介：

Test the influence of azacytidine on leukemic cells after xenotransplantation Overall design: ex vivo treatment

应用场景：

创建时间：

2023-11-15

药物组合筛选

药物协同效应评估

NOTE: Combination Index (CI) values for 17-AAG with cisplatin at a constant ratio (1:175) as determined using the method of Chou and Talalay. CI = 1: additive effect; CI 1: antagonism.

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Combination index values for combinatorial treatment of curcumin and emodin in human cervical cancer cells.

药物协同效应评估

宫颈癌体外药敏实验

SiHa and HeLa cells treated with different concentration combinations of curcumin and emodin were assayed for cell viability by resazurin reduction method at 48h and combination indices (CI) were calc

Figshare2015-12-03 更新20

Ranking of 20 in-house measured combinations based on STE scores calculated from the most synergistic area of dose-response matrix in T-PLL and healthy control cells.

药物协同效应评估

白血病研究

Ranking of 20 in-house measured combinations based on STE scores calculated from the most synergistic area of dose-response matrix in T-PLL and healthy control cells.

Figshare2020-02-03 更新10

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer

癌症药物组合筛选

药物协同效应评估

High-throughput drug screening has facilitated the discovery of drug combinations in cancer. Many existing studies adopted a full matrix design, aiming for the characterization of drug pair effects fo

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Supplementary Table S5 from Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression

滤泡性淋巴瘤

药物协同效应评估

Excess-over-BLISS (EOB) scores for drug combinations

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