Transcriptome profiling data of urothelial cell carcinoma (UCC) persistently infected with oncolytic Newcastle disease virus

Newcastle disease virus (NDV) is an avian virus that selectively replicates and kills many different types of cancer cells and is being developed for cancer treatment. Our aim was to establish persistent infection in EJ28 and TCCSUP bladder cancer cells and identify the dysregulated genes and disrupted molecular pathways associated with persistent infection. mRNA transcriptome profiles of bladder cancer cell lines persistently infected with oncolytic Newcastle disease virus (NDV) AF2240 strain (EJ28Pi and TCCSUPPi) and uninfected (control) EJ28 and TCCSUP bladder cancer cell lines were generated in triplicate by deep sequencing using Illumina HiSeq 2000.