For clinical trials in patients with asthma, chronic obstructive pulmonary disease, and relapsing-remitting multiple sclerosis, regulatory guidelines state that a noninferiority clinical trial is an o
When we designed the Valkyrie trial several different considerations were made on how to calculate the number of patients to be recruited for the trial. In the end, the decision fell on the way as des
Supplemental material, sj-txt-3-smm-10.1177_09622802211007522 for Estimation of required sample size for external validation of risk models for binary outcomes by Menelaos Pavlou, Chen Qu, Rumana Z Om